Competitive Comparison
See how the Resonance MTX Device stacks up against current immunoassays.
Product Comparison: Current Immunoassays (USA)
| Product X (Resonance) | ARK Immunoassay | Enzo ELISA Kit (RUO) | |
|---|---|---|---|
| Sensitivity | 0.04 μmol/L | 0.04 μmol/L | 0.087 ng/ml |
| Specificity | ✓ No cross-reactivity to DAMPA, leucovorin or any other typical blood species | ✗ Cross-reacts to DAMPA (76.3% to 100%) | ✗ Cross-reacts to DAMPA (20.5%) |
| CV% | ≤ 20% CV | ≤ 10% CV | ≤ 20% CV |
| Detection Range | 0.04–1000 μmol/L | 0.04–1.20 μmol/L | 0.13–1000 ng/mL (0.0003–2 μmol/L) |
| Sample Requirements | Venous Blood (Launch); Capillary blood (Life Cycle) | Serum and plasma | Serum, plasma, urine |
| Site of Testing | ✓ Bedside by a healthcare professional | ✗ Hospital lab by trained technician | ✗ Hospital lab by trained technician |
| Time to Result | ✓ ≤ 10 minutes | ✗ ~2 hours | ✗ 1.5 hours |
| Sample Prep & Workflow | ✓ Lateral flow device → buffer addition | ✗ Centrifuge → Dilute → Mass spectrometer | ✗ Centrifuge → dilute → run ELISA |
Key Differentiators
✓
No DAMPA cross-reactivity Competitors show 20–100% cross-reactivity
✓
Bedside testing No hospital lab or specialized technician needed
✓
≤ 10 minutes Versus 1.5–2 hours with immunoassays
✓
Simple workflow No centrifuge, no serial dilution required
Sources:
1. ARK Immunoassay FDA Decision Summary. 2011.
2. ARK Package Insert. Accessed July 2019.
3. Enzo Product Manual. 2015.